| Reston to Scottsboro (Alabama) | 565.61 mi (910.26 km) |
| Reston to Scottsdale (Arizona) | 1,943.81 mi (3,128.26 km) |
| Reston to Scranton (Pennsylvania) | 191.41 mi (308.05 km) |
| Reston to Seabrook (Maryland) | 26.72 mi (43.01 km) |
| Reston to Seabrook (Texas) | 1,196.03 mi (1,924.82 km) |
| Reston to Seaford (New York) | 236.47 mi (380.56 km) |
| Reston to Seagoville (Texas) | 1,157.64 mi (1,863.04 km) |
| Reston to Seal Beach (California) | 2,275.39 mi (3,661.89 km) |
| Reston to Searcy (Arkansas) | 832.26 mi (1,339.40 km) |
| Reston to Seaside (California) | 2,409.67 mi (3,877.99 km) |
| Reston to SeaTac (Washington) | 2,304.55 mi (3,708.82 km) |
| Reston to Seattle (Washington) | 2,305.35 mi (3,710.10 km) |
| Reston to Sebastian (Florida) | 792.38 mi (1,275.21 km) |
| Reston to Sebring (Florida) | 827.21 mi (1,331.26 km) |
| Reston to Secaucus (New Jersey) | 215.08 mi (346.14 km) |
