| Reston to Santa Rosa (California) | 2,420.39 mi (3,895.25 km) |
| Reston to Santaquin (Utah) | 1,827.50 mi (2,941.08 km) |
| Reston to Santee (California) | 2,240.00 mi (3,604.93 km) |
| Reston to Sapulpa (Oklahoma) | 1,046.20 mi (1,683.69 km) |
| Reston to Saraland (Alabama) | 826.36 mi (1,329.89 km) |
| Reston to Sarasota (Florida) | 856.31 mi (1,378.10 km) |
| Reston to Sarasota Springs (Florida) | 856.90 mi (1,379.04 km) |
| Reston to Saratoga (California) | 2,407.32 mi (3,874.21 km) |
| Reston to Saratoga Springs (New York) | 339.87 mi (546.96 km) |
| Reston to Saratoga Springs (Utah) | 1,829.93 mi (2,945.00 km) |
| Reston to Sartell (Minnesota) | 975.18 mi (1,569.40 km) |
| Reston to Satellite Beach (Florida) | 767.32 mi (1,234.89 km) |
| Reston to Sauk Rapids (Minnesota) | 971.65 mi (1,563.72 km) |
| Reston to Sault Ste. Marie (Michigan) | 630.34 mi (1,014.43 km) |
| Reston to Savage (Minnesota) | 914.56 mi (1,471.84 km) |
