| Reston to Sanford (Maine) | 461.20 mi (742.23 km) |
| Reston to Sanford (North Carolina) | 259.54 mi (417.70 km) |
| Reston to Sanger (California) | 2,288.40 mi (3,682.82 km) |
| Reston to Santa Ana (California) | 2,265.67 mi (3,646.24 km) |
| Reston to Santa Barbara (California) | 2,347.24 mi (3,777.52 km) |
| Reston to Santa Clara (California) | 2,402.34 mi (3,866.19 km) |
| Reston to Santa Clara (Oregon) | 2,364.01 mi (3,804.51 km) |
| Reston to Santa Clarita (California) | 2,282.04 mi (3,672.60 km) |
| Reston to Santa Cruz (California) | 2,413.62 mi (3,884.34 km) |
| Reston to Santa Fe (New Mexico) | 1,583.43 mi (2,548.29 km) |
| Reston to Santa Fe (Texas) | 1,207.55 mi (1,943.36 km) |
| Reston to Santa Fe Springs (California) | 2,270.51 mi (3,654.03 km) |
| Reston to Santa Maria (California) | 2,373.92 mi (3,820.45 km) |
| Reston to Santa Monica (California) | 2,290.72 mi (3,686.55 km) |
| Reston to Santa Paula (California) | 2,314.01 mi (3,724.03 km) |
