| Reston to Oskaloosa (Iowa) | 822.97 mi (1,324.43 km) |
| Reston to Oswego (Illinois) | 608.55 mi (979.36 km) |
| Reston to Oswego (New York) | 314.14 mi (505.55 km) |
| Reston to Otsego (Minnesota) | 939.04 mi (1,511.23 km) |
| Reston to Ottawa (Illinois) | 628.09 mi (1,010.82 km) |
| Reston to Ottawa (Kansas) | 963.90 mi (1,551.24 km) |
| Reston to Ottumwa (Iowa) | 809.59 mi (1,302.91 km) |
| Reston to Overland (Missouri) | 700.63 mi (1,127.56 km) |
| Reston to Overland Park (Kansas) | 930.80 mi (1,497.98 km) |
| Reston to Overlea (Maryland) | 52.83 mi (85.02 km) |
| Reston to Oviedo (Florida) | 744.29 mi (1,197.82 km) |
| Reston to Owasso (Oklahoma) | 1,026.36 mi (1,651.77 km) |
| Reston to Owatonna (Minnesota) | 893.34 mi (1,437.70 km) |
| Reston to Owensboro (Kentucky) | 535.52 mi (861.84 km) |
| Reston to Owings Mills (Maryland) | 43.60 mi (70.17 km) |
