| Reston to Orangeburg (South Carolina) | 424.96 mi (683.91 km) |
| Reston to Orangevale (California) | 2,338.53 mi (3,763.50 km) |
| Reston to Orchards (Washington) | 2,322.88 mi (3,738.31 km) |
| Reston to Orcutt (California) | 2,374.30 mi (3,821.07 km) |
| Reston to Oregon (Ohio) | 370.97 mi (597.02 km) |
| Reston to Oregon (Wisconsin) | 685.15 mi (1,102.64 km) |
| Reston to Oregon City (Oregon) | 2,328.01 mi (3,746.57 km) |
| Reston to Orem (Utah) | 1,819.15 mi (2,927.63 km) |
| Reston to Orinda (California) | 2,403.38 mi (3,867.86 km) |
| Reston to Orland Park (Illinois) | 583.48 mi (939.02 km) |
| Reston to Orlando (Florida) | 758.83 mi (1,221.21 km) |
| Reston to Ormond Beach (Florida) | 700.38 mi (1,127.16 km) |
| Reston to Oro Valley (Arizona) | 1,928.80 mi (3,104.10 km) |
| Reston to Oroville (California) | 2,342.72 mi (3,770.24 km) |
| Reston to Oshkosh (Wisconsin) | 677.24 mi (1,089.90 km) |
