| Reston to Olympia (Washington) | 2,333.79 mi (3,755.87 km) |
| Reston to Olympia Heights (Florida) | 930.20 mi (1,497.01 km) |
| Reston to Omaha (Nebraska) | 999.40 mi (1,608.38 km) |
| Reston to On Top of the World Designated Place (Florida) | 736.31 mi (1,184.98 km) |
| Reston to Onalaska (Wisconsin) | 793.77 mi (1,277.45 km) |
| Reston to Oneida (New York) | 298.35 mi (480.15 km) |
| Reston to Oneonta (New York) | 270.00 mi (434.53 km) |
| Reston to Ontario (California) | 2,243.47 mi (3,610.51 km) |
| Reston to Ontario (Oregon) | 2,060.57 mi (3,316.16 km) |
| Reston to Opa-locka (Florida) | 917.34 mi (1,476.31 km) |
| Reston to Opelika (Alabama) | 625.03 mi (1,005.88 km) |
| Reston to Opelousas (Louisiana) | 1,017.09 mi (1,636.85 km) |
| Reston to Orange (California) | 2,260.78 mi (3,638.38 km) |
| Reston to Orange (Texas) | 1,112.97 mi (1,791.16 km) |
| Reston to Orange City (Florida) | 727.70 mi (1,171.13 km) |
