| Reston to Enterprise (Nevada) | 2,072.05 mi (3,334.64 km) |
| Reston to Enumclaw (Washington) | 2,290.72 mi (3,686.56 km) |
| Reston to Ephrata (Pennsylvania) | 105.30 mi (169.46 km) |
| Reston to Erie (Colorado) | 1,472.55 mi (2,369.84 km) |
| Reston to Erie (Pennsylvania) | 261.48 mi (420.82 km) |
| Reston to Erlanger (Kentucky) | 388.80 mi (625.71 km) |
| Reston to Escanaba (Michigan) | 683.30 mi (1,099.66 km) |
| Reston to Escondido (California) | 2,237.43 mi (3,600.80 km) |
| Reston to Española (New Mexico) | 1,581.39 mi (2,545.00 km) |
| Reston to Essex (Maryland) | 54.09 mi (87.06 km) |
| Reston to Essex Junction (Vermont) | 440.50 mi (708.92 km) |
| Reston to Estelle (Louisiana) | 959.82 mi (1,544.68 km) |
| Reston to Estero (Florida) | 902.71 mi (1,452.77 km) |
| Reston to Euclid (Ohio) | 285.73 mi (459.84 km) |
| Reston to Eufaula (Alabama) | 654.91 mi (1,053.98 km) |
