| Reston to Sestu | 4,434.37 mi (7,136.43 km) |
| Reston to Settimo Torinese | 4,180.76 mi (6,728.29 km) |
| Reston to Seveso | 4,223.66 mi (6,797.33 km) |
| Reston to Sezze | 4,535.79 mi (7,299.65 km) |
| Reston to Siano | 4,633.15 mi (7,456.33 km) |
| Reston to Siena | 4,395.65 mi (7,074.12 km) |
| Reston to Signa | 4,369.70 mi (7,032.35 km) |
| Reston to Silea | 4,357.49 mi (7,012.70 km) |
| Reston to Silvi Paese | 4,543.92 mi (7,312.73 km) |
| Reston to Sinalunga | 4,416.68 mi (7,107.96 km) |
| Reston to Siniscola | 4,417.59 mi (7,109.42 km) |
| Reston to Sinnai | 4,439.39 mi (7,144.51 km) |
| Reston to Siracusa | 4,801.10 mi (7,726.62 km) |
| Reston to Solaro | 4,222.28 mi (6,795.10 km) |
| Reston to Soliera | 4,329.92 mi (6,968.34 km) |
