| Rapid City to Southern Pines (North Carolina) | 1,401.13 mi (2,254.90 km) |
| Rapid City to Southfield (Michigan) | 1,007.62 mi (1,621.61 km) |
| Rapid City to Southgate (Michigan) | 1,014.76 mi (1,633.09 km) |
| Rapid City to Southlake (Texas) | 834.67 mi (1,343.28 km) |
| Rapid City to Spanaway (Washington) | 949.20 mi (1,527.59 km) |
| Rapid City to Spanish Fork (Utah) | 510.78 mi (822.02 km) |
| Rapid City to Spanish Lake (Missouri) | 765.33 mi (1,231.69 km) |
| Rapid City to Spanish Springs (Nevada) | 897.79 mi (1,444.85 km) |
| Rapid City to Sparks (Nevada) | 902.50 mi (1,452.43 km) |
| Rapid City to Spartanburg (South Carolina) | 1,293.09 mi (2,081.02 km) |
| Rapid City to Spearfish (South Dakota) | 41.30 mi (66.47 km) |
| Rapid City to Speedway (Indiana) | 919.09 mi (1,479.13 km) |
| Rapid City to Spencer (Iowa) | 408.43 mi (657.30 km) |
| Rapid City to Spokane (Washington) | 726.20 mi (1,168.70 km) |
| Rapid City to Spokane Valley (Washington) | 717.20 mi (1,154.22 km) |
