| Rapid City to Enterprise (Nevada) | 843.24 mi (1,357.07 km) |
| Rapid City to Enumclaw (Washington) | 929.71 mi (1,496.22 km) |
| Rapid City to Ephrata (Pennsylvania) | 1,404.79 mi (2,260.79 km) |
| Rapid City to Erie (Colorado) | 293.73 mi (472.72 km) |
| Rapid City to Erie (Pennsylvania) | 1,171.74 mi (1,885.73 km) |
| Rapid City to Erlanger (Kentucky) | 1,022.38 mi (1,645.35 km) |
| Rapid City to Escanaba (Michigan) | 796.36 mi (1,281.62 km) |
| Rapid City to Escondido (California) | 1,060.38 mi (1,706.52 km) |
| Rapid City to Española (New Mexico) | 577.29 mi (929.06 km) |
| Rapid City to Essex (Maryland) | 1,413.54 mi (2,274.88 km) |
| Rapid City to Essex Junction (Vermont) | 1,481.04 mi (2,383.51 km) |
| Rapid City to Estelle (Louisiana) | 1,217.66 mi (1,959.63 km) |
| Rapid City to Estero (Florida) | 1,706.71 mi (2,746.69 km) |
| Rapid City to Euclid (Ohio) | 1,109.59 mi (1,785.71 km) |
| Rapid City to Eufaula (Alabama) | 1,288.74 mi (2,074.03 km) |
