| Rancho Santa Margarita to West St. Paul (Minnesota) | 1,516.06 mi (2,439.87 km) |
| Rancho Santa Margarita to West University Place (Texas) | 1,328.48 mi (2,137.98 km) |
| Rancho Santa Margarita to West Valley City (Utah) | 576.20 mi (927.30 km) |
| Rancho Santa Margarita to West Whittier-Los Nietos (California) | 35.97 mi (57.88 km) |
| Rancho Santa Margarita to Westbrook (Maine) | 2,604.37 mi (4,191.33 km) |
| Rancho Santa Margarita to Westbury (New York) | 2,445.45 mi (3,935.57 km) |
| Rancho Santa Margarita to Westchase (Florida) | 2,100.64 mi (3,380.66 km) |
| Rancho Santa Margarita to Westchester (Florida) | 2,287.96 mi (3,682.11 km) |
| Rancho Santa Margarita to Westchester (Illinois) | 1,709.41 mi (2,751.03 km) |
| Rancho Santa Margarita to Western Springs (Illinois) | 1,708.36 mi (2,749.34 km) |
| Rancho Santa Margarita to Westerville (Ohio) | 1,955.20 mi (3,146.59 km) |
| Rancho Santa Margarita to Westfield (Indiana) | 1,784.27 mi (2,871.51 km) |
| Rancho Santa Margarita to Westfield (Massachusetts) | 2,485.04 mi (3,999.28 km) |
| Rancho Santa Margarita to Westfield (New Jersey) | 2,406.34 mi (3,872.63 km) |
| Rancho Santa Margarita to Westlake (Ohio) | 2,011.82 mi (3,237.71 km) |
