| Rancho Santa Margarita to Vega Baja (Puerto Rico) | 3,311.12 mi (5,328.74 km) |
| Rancho Santa Margarita to Venice (Florida) | 2,134.36 mi (3,434.92 km) |
| Rancho Santa Margarita to Verde Village (Arizona) | 328.92 mi (529.34 km) |
| Rancho Santa Margarita to Vermilion (Ohio) | 1,991.36 mi (3,204.78 km) |
| Rancho Santa Margarita to Vermillion (South Dakota) | 1,283.15 mi (2,065.03 km) |
| Rancho Santa Margarita to Vernon (Texas) | 1,048.73 mi (1,687.77 km) |
| Rancho Santa Margarita to Vernon Hills (Illinois) | 1,710.51 mi (2,752.80 km) |
| Rancho Santa Margarita to Vero Beach (Florida) | 2,237.85 mi (3,601.46 km) |
| Rancho Santa Margarita to Vero Beach South (Florida) | 2,237.29 mi (3,600.57 km) |
| Rancho Santa Margarita to Verona (Wisconsin) | 1,643.03 mi (2,644.20 km) |
| Rancho Santa Margarita to Versailles (Kentucky) | 1,856.48 mi (2,987.71 km) |
| Rancho Santa Margarita to Vestavia Hills (Alabama) | 1,770.25 mi (2,848.94 km) |
| Rancho Santa Margarita to Vicksburg (Mississippi) | 1,546.69 mi (2,489.16 km) |
| Rancho Santa Margarita to Victoria (Minnesota) | 1,489.18 mi (2,396.61 km) |
| Rancho Santa Margarita to Victoria (Texas) | 1,259.85 mi (2,027.53 km) |
