| Rancho Santa Margarita to Valencia West (Arizona) | 390.23 mi (628.01 km) |
| Rancho Santa Margarita to Valinda (California) | 34.01 mi (54.74 km) |
| Rancho Santa Margarita to Valle Vista (California) | 41.64 mi (67.01 km) |
| Rancho Santa Margarita to Vallejo (California) | 403.85 mi (649.94 km) |
| Rancho Santa Margarita to Valley (Alabama) | 1,866.96 mi (3,004.58 km) |
| Rancho Santa Margarita to Valley Center (California) | 43.47 mi (69.95 km) |
| Rancho Santa Margarita to Valley Falls (Rhode Island) | 2,555.50 mi (4,112.68 km) |
| Rancho Santa Margarita to Valley Stream (New York) | 2,439.75 mi (3,926.40 km) |
| Rancho Santa Margarita to Valparaiso (Indiana) | 1,748.31 mi (2,813.64 km) |
| Rancho Santa Margarita to Valrico (Florida) | 2,125.83 mi (3,421.20 km) |
| Rancho Santa Margarita to Van Buren (Arkansas) | 1,325.90 mi (2,133.83 km) |
| Rancho Santa Margarita to Van Wert (Ohio) | 1,870.86 mi (3,010.86 km) |
| Rancho Santa Margarita to Vancouver (Washington) | 870.58 mi (1,401.06 km) |
| Rancho Santa Margarita to Vandalia (Ohio) | 1,887.24 mi (3,037.22 km) |
| Rancho Santa Margarita to Vashon (Washington) | 985.42 mi (1,585.88 km) |
