| Rancho Santa Margarita to Tulare (California) | 202.98 mi (326.67 km) |
| Rancho Santa Margarita to Tullahoma (Tennessee) | 1,783.46 mi (2,870.20 km) |
| Rancho Santa Margarita to Tulsa (Oklahoma) | 1,239.07 mi (1,994.09 km) |
| Rancho Santa Margarita to Tumwater (Washington) | 963.91 mi (1,551.26 km) |
| Rancho Santa Margarita to Tupelo (Mississippi) | 1,649.51 mi (2,654.63 km) |
| Rancho Santa Margarita to Turlock (California) | 324.29 mi (521.89 km) |
| Rancho Santa Margarita to Tuscaloosa (Alabama) | 1,728.02 mi (2,780.97 km) |
| Rancho Santa Margarita to Tustin (California) | 13.98 mi (22.50 km) |
| Rancho Santa Margarita to Twentynine Palms (California) | 94.87 mi (152.68 km) |
| Rancho Santa Margarita to Twin Falls (Idaho) | 640.20 mi (1,030.30 km) |
| Rancho Santa Margarita to Twin Rivers (New Jersey) | 2,399.84 mi (3,862.16 km) |
| Rancho Santa Margarita to Twinsburg (Ohio) | 2,036.32 mi (3,277.14 km) |
| Rancho Santa Margarita to Two Rivers (Wisconsin) | 1,757.50 mi (2,828.42 km) |
| Rancho Santa Margarita to Tyler (Texas) | 1,292.83 mi (2,080.61 km) |
| Rancho Santa Margarita to Tysons (Virginia) | 2,259.58 mi (3,636.44 km) |
