| Rancho Santa Margarita to Rosemont (California) | 399.11 mi (642.30 km) |
| Rancho Santa Margarita to Rosemount (Minnesota) | 1,512.90 mi (2,434.78 km) |
| Rancho Santa Margarita to Rosenberg (Texas) | 1,309.74 mi (2,107.83 km) |
| Rancho Santa Margarita to Roseville (California) | 411.10 mi (661.61 km) |
| Rancho Santa Margarita to Roseville (Michigan) | 1,966.89 mi (3,165.40 km) |
| Rancho Santa Margarita to Roseville (Minnesota) | 1,515.98 mi (2,439.73 km) |
| Rancho Santa Margarita to Rossmoor (California) | 29.72 mi (47.83 km) |
| Rancho Santa Margarita to Rossville (Maryland) | 2,298.00 mi (3,698.27 km) |
| Rancho Santa Margarita to Roswell (Georgia) | 1,899.84 mi (3,057.50 km) |
| Rancho Santa Margarita to Roswell (New Mexico) | 752.70 mi (1,211.35 km) |
| Rancho Santa Margarita to Round Lake (Illinois) | 1,704.62 mi (2,743.33 km) |
| Rancho Santa Margarita to Round Lake Beach (Illinois) | 1,706.33 mi (2,746.08 km) |
| Rancho Santa Margarita to Round Rock (Texas) | 1,184.64 mi (1,906.50 km) |
| Rancho Santa Margarita to Rowland Heights (California) | 28.86 mi (46.45 km) |
| Rancho Santa Margarita to Rowlett (Texas) | 1,214.88 mi (1,955.17 km) |
