| Rancho Santa Margarita to Pottstown (Pennsylvania) | 2,339.16 mi (3,764.51 km) |
| Rancho Santa Margarita to Pottsville (Pennsylvania) | 2,308.54 mi (3,715.24 km) |
| Rancho Santa Margarita to Poughkeepsie (New York) | 2,425.88 mi (3,904.08 km) |
| Rancho Santa Margarita to Poulsbo (Washington) | 1,009.48 mi (1,624.60 km) |
| Rancho Santa Margarita to Poway (California) | 55.68 mi (89.62 km) |
| Rancho Santa Margarita to Powder Springs (Georgia) | 1,882.81 mi (3,030.09 km) |
| Rancho Santa Margarita to Powell (Ohio) | 1,946.78 mi (3,133.04 km) |
| Rancho Santa Margarita to Powell (Tennessee) | 1,901.64 mi (3,060.39 km) |
| Rancho Santa Margarita to Prairie Ridge (Washington) | 963.26 mi (1,550.22 km) |
| Rancho Santa Margarita to Prairie Village (Kansas) | 1,326.88 mi (2,135.41 km) |
| Rancho Santa Margarita to Prairieville (Louisiana) | 1,573.80 mi (2,532.79 km) |
| Rancho Santa Margarita to Prattville (Alabama) | 1,798.62 mi (2,894.61 km) |
| Rancho Santa Margarita to Preakness (New Jersey) | 2,411.75 mi (3,881.33 km) |
| Rancho Santa Margarita to Prescott (Arizona) | 301.94 mi (485.92 km) |
| Rancho Santa Margarita to Prescott Valley (Arizona) | 309.30 mi (497.77 km) |
