| Rancho Santa Margarita to Petaluma (California) | 424.81 mi (683.66 km) |
| Rancho Santa Margarita to Petersburg (Virginia) | 2,260.47 mi (3,637.87 km) |
| Rancho Santa Margarita to Pflugerville (Texas) | 1,189.64 mi (1,914.53 km) |
| Rancho Santa Margarita to Pharr (Texas) | 1,268.96 mi (2,042.19 km) |
| Rancho Santa Margarita to Phelan (California) | 55.99 mi (90.10 km) |
| Rancho Santa Margarita to Phenix City (Alabama) | 1,880.51 mi (3,026.38 km) |
| Rancho Santa Margarita to Philadelphia (Pennsylvania) | 2,366.88 mi (3,809.13 km) |
| Rancho Santa Margarita to Phillipsburg (New Jersey) | 2,362.31 mi (3,801.77 km) |
| Rancho Santa Margarita to Phoenix (Arizona) | 317.06 mi (510.25 km) |
| Rancho Santa Margarita to Phoenixville (Pennsylvania) | 2,346.06 mi (3,775.61 km) |
| Rancho Santa Margarita to Picayune (Mississippi) | 1,643.80 mi (2,645.44 km) |
| Rancho Santa Margarita to Pickerington (Ohio) | 1,962.77 mi (3,158.78 km) |
| Rancho Santa Margarita to Pico Rivera (California) | 37.47 mi (60.31 km) |
| Rancho Santa Margarita to Piedmont (California) | 388.88 mi (625.85 km) |
| Rancho Santa Margarita to Pierre (South Dakota) | 1,183.87 mi (1,905.25 km) |
