| Rancho Santa Margarita to Myrtle Grove (Florida) | 1,782.19 mi (2,868.16 km) |
| Rancho Santa Margarita to Myrtle Grove (North Carolina) | 2,263.83 mi (3,643.28 km) |
| Rancho Santa Margarita to Nacogdoches (Texas) | 1,339.80 mi (2,156.20 km) |
| Rancho Santa Margarita to Nampa (Idaho) | 689.91 mi (1,110.30 km) |
| Rancho Santa Margarita to Nanakuli (Hawaii) | 2,605.57 mi (4,193.26 km) |
| Rancho Santa Margarita to Nanticoke (Pennsylvania) | 2,318.81 mi (3,731.76 km) |
| Rancho Santa Margarita to Nanuet (New York) | 2,422.21 mi (3,898.18 km) |
| Rancho Santa Margarita to Napa (California) | 415.88 mi (669.30 km) |
| Rancho Santa Margarita to Naperville (Illinois) | 1,694.26 mi (2,726.65 km) |
| Rancho Santa Margarita to Naples (Florida) | 2,194.56 mi (3,531.81 km) |
| Rancho Santa Margarita to Naranja (Florida) | 2,290.14 mi (3,685.63 km) |
| Rancho Santa Margarita to Nashua (New Hampshire) | 2,548.47 mi (4,101.37 km) |
| Rancho Santa Margarita to Nashville (Tennessee) | 1,747.60 mi (2,812.49 km) |
| Rancho Santa Margarita to Natchez (Mississippi) | 1,528.68 mi (2,460.17 km) |
| Rancho Santa Margarita to Natchitoches (Louisiana) | 1,427.57 mi (2,297.44 km) |
