| Rancho Santa Margarita to Montgomeryville (Pennsylvania) | 2,360.44 mi (3,798.77 km) |
| Rancho Santa Margarita to Monticello (Minnesota) | 1,494.99 mi (2,405.96 km) |
| Rancho Santa Margarita to Montrose (Colorado) | 637.98 mi (1,026.73 km) |
| Rancho Santa Margarita to Moody (Alabama) | 1,782.75 mi (2,869.05 km) |
| Rancho Santa Margarita to Moore (Oklahoma) | 1,150.10 mi (1,850.91 km) |
| Rancho Santa Margarita to Moorestown-Lenola (New Jersey) | 2,376.00 mi (3,823.80 km) |
| Rancho Santa Margarita to Mooresville (North Carolina) | 2,083.38 mi (3,352.88 km) |
| Rancho Santa Margarita to Moorhead (Minnesota) | 1,422.30 mi (2,288.97 km) |
| Rancho Santa Margarita to Moorpark (California) | 86.07 mi (138.51 km) |
| Rancho Santa Margarita to Moraga (California) | 385.97 mi (621.17 km) |
| Rancho Santa Margarita to Moreno Valley (California) | 30.36 mi (48.85 km) |
| Rancho Santa Margarita to Morgan City (Louisiana) | 1,571.97 mi (2,529.84 km) |
| Rancho Santa Margarita to Morgan Hill (California) | 332.16 mi (534.56 km) |
| Rancho Santa Margarita to Morganton (North Carolina) | 2,033.41 mi (3,272.46 km) |
| Rancho Santa Margarita to Morgantown (West Virginia) | 2,112.47 mi (3,399.70 km) |
