| Rancho Santa Margarita to Middletown (New York) | 2,400.31 mi (3,862.92 km) |
| Rancho Santa Margarita to Middletown (Ohio) | 1,877.02 mi (3,020.78 km) |
| Rancho Santa Margarita to Midland (Michigan) | 1,913.12 mi (3,078.87 km) |
| Rancho Santa Margarita to Midland (Texas) | 904.96 mi (1,456.39 km) |
| Rancho Santa Margarita to Midlothian (Illinois) | 1,715.37 mi (2,760.62 km) |
| Rancho Santa Margarita to Midlothian (Texas) | 1,194.34 mi (1,922.10 km) |
| Rancho Santa Margarita to Midlothian (Virginia) | 2,244.26 mi (3,611.79 km) |
| Rancho Santa Margarita to Midvale (Utah) | 575.54 mi (926.23 km) |
| Rancho Santa Margarita to Midway (Florida) | 1,798.26 mi (2,894.03 km) |
| Rancho Santa Margarita to Midwest City (Oklahoma) | 1,156.04 mi (1,860.46 km) |
| Rancho Santa Margarita to Milford (Delaware) | 2,356.42 mi (3,792.30 km) |
| Rancho Santa Margarita to Milford city (Connecticut) | 2,471.39 mi (3,977.32 km) |
| Rancho Santa Margarita to Milford Mill (Maryland) | 2,282.57 mi (3,673.44 km) |
| Rancho Santa Margarita to Mililani Mauka (Hawaii) | 2,594.27 mi (4,175.07 km) |
| Rancho Santa Margarita to Mililani Town (Hawaii) | 2,596.34 mi (4,178.40 km) |
