| Rancho Santa Margarita to Miami Gardens (Florida) | 2,289.05 mi (3,683.87 km) |
| Rancho Santa Margarita to Miami Lakes (Florida) | 2,285.34 mi (3,677.90 km) |
| Rancho Santa Margarita to Miami Shores (Florida) | 2,294.78 mi (3,693.10 km) |
| Rancho Santa Margarita to Miami Springs (Florida) | 2,289.64 mi (3,684.82 km) |
| Rancho Santa Margarita to Miamisburg (Ohio) | 1,882.32 mi (3,029.30 km) |
| Rancho Santa Margarita to Michigan City (Indiana) | 1,759.88 mi (2,832.26 km) |
| Rancho Santa Margarita to Middle Island (New York) | 2,478.62 mi (3,988.95 km) |
| Rancho Santa Margarita to Middle River (Maryland) | 2,300.80 mi (3,702.77 km) |
| Rancho Santa Margarita to Middle Valley (Tennessee) | 1,842.05 mi (2,964.49 km) |
| Rancho Santa Margarita to Middleburg (Florida) | 2,099.51 mi (3,378.83 km) |
| Rancho Santa Margarita to Middleburg Heights (Ohio) | 2,017.36 mi (3,246.63 km) |
| Rancho Santa Margarita to Middlesex (New Jersey) | 2,398.30 mi (3,859.70 km) |
| Rancho Santa Margarita to Middleton (Wisconsin) | 1,646.56 mi (2,649.88 km) |
| Rancho Santa Margarita to Middletown (Connecticut) | 2,491.57 mi (4,009.79 km) |
| Rancho Santa Margarita to Middletown (Delaware) | 2,338.07 mi (3,762.76 km) |
