| Rancho Santa Margarita to Mattoon (Illinois) | 1,664.22 mi (2,678.30 km) |
| Rancho Santa Margarita to Mauldin (South Carolina) | 2,007.99 mi (3,231.54 km) |
| Rancho Santa Margarita to Maumee (Ohio) | 1,923.04 mi (3,094.83 km) |
| Rancho Santa Margarita to Maumelle (Arkansas) | 1,437.98 mi (2,314.20 km) |
| Rancho Santa Margarita to Mayagüez (Puerto Rico) | 3,276.84 mi (5,273.57 km) |
| Rancho Santa Margarita to Mayfield Heights (Ohio) | 2,036.70 mi (3,277.75 km) |
| Rancho Santa Margarita to Mays Chapel (Maryland) | 2,288.39 mi (3,682.81 km) |
| Rancho Santa Margarita to Maywood (California) | 41.84 mi (67.34 km) |
| Rancho Santa Margarita to Maywood (Illinois) | 1,712.12 mi (2,755.39 km) |
| Rancho Santa Margarita to McAlester (Oklahoma) | 1,246.80 mi (2,006.52 km) |
| Rancho Santa Margarita to McAllen (Texas) | 1,264.02 mi (2,034.25 km) |
| Rancho Santa Margarita to McCalla (Alabama) | 1,755.57 mi (2,825.32 km) |
| Rancho Santa Margarita to McComb (Mississippi) | 1,585.90 mi (2,552.25 km) |
| Rancho Santa Margarita to McDonough (Georgia) | 1,917.86 mi (3,086.50 km) |
| Rancho Santa Margarita to McFarland (California) | 169.42 mi (272.65 km) |
