| Rancho Santa Margarita to Mankato (Minnesota) | 1,456.37 mi (2,343.79 km) |
| Rancho Santa Margarita to Manor (Texas) | 1,195.98 mi (1,924.75 km) |
| Rancho Santa Margarita to Manorville (New York) | 2,486.75 mi (4,002.04 km) |
| Rancho Santa Margarita to Mansfield (Ohio) | 1,977.88 mi (3,183.09 km) |
| Rancho Santa Margarita to Mansfield (Texas) | 1,185.59 mi (1,908.02 km) |
| Rancho Santa Margarita to Manteca (California) | 352.16 mi (566.75 km) |
| Rancho Santa Margarita to Manville (New Jersey) | 2,393.78 mi (3,852.42 km) |
| Rancho Santa Margarita to Maple Grove (Minnesota) | 1,504.68 mi (2,421.55 km) |
| Rancho Santa Margarita to Maple Heights (Ohio) | 2,030.60 mi (3,267.93 km) |
| Rancho Santa Margarita to Maple Valley (Washington) | 976.73 mi (1,571.89 km) |
| Rancho Santa Margarita to Mapleton (Utah) | 558.04 mi (898.09 km) |
| Rancho Santa Margarita to Maplewood (Minnesota) | 1,521.00 mi (2,447.81 km) |
| Rancho Santa Margarita to Marana (Arizona) | 382.18 mi (615.06 km) |
| Rancho Santa Margarita to Marco Island (Florida) | 2,205.71 mi (3,549.74 km) |
| Rancho Santa Margarita to Margate (Florida) | 2,282.89 mi (3,673.96 km) |
