| Rancho Santa Margarita to Lovington (New Mexico) | 825.24 mi (1,328.10 km) |
| Rancho Santa Margarita to Lowell (Indiana) | 1,727.58 mi (2,780.27 km) |
| Rancho Santa Margarita to Lowell (Massachusetts) | 2,557.27 mi (4,115.53 km) |
| Rancho Santa Margarita to Lower Burrell (Pennsylvania) | 2,124.80 mi (3,419.54 km) |
| Rancho Santa Margarita to Lowes Island (Virginia) | 2,252.37 mi (3,624.84 km) |
| Rancho Santa Margarita to Lubbock (Texas) | 903.30 mi (1,453.73 km) |
| Rancho Santa Margarita to Lufkin (Texas) | 1,339.87 mi (2,156.31 km) |
| Rancho Santa Margarita to Luling (Louisiana) | 1,616.38 mi (2,601.31 km) |
| Rancho Santa Margarita to Lumberton (North Carolina) | 2,193.99 mi (3,530.88 km) |
| Rancho Santa Margarita to Lumberton (Texas) | 1,388.07 mi (2,233.89 km) |
| Rancho Santa Margarita to Lutz (Florida) | 2,108.27 mi (3,392.93 km) |
| Rancho Santa Margarita to Lynbrook (New York) | 2,441.35 mi (3,928.97 km) |
| Rancho Santa Margarita to Lynchburg (Virginia) | 2,160.72 mi (3,477.35 km) |
| Rancho Santa Margarita to Lynden (Washington) | 1,087.42 mi (1,750.03 km) |
| Rancho Santa Margarita to Lyndhurst (Ohio) | 2,034.69 mi (3,274.52 km) |
