| Rancho Santa Margarita to Laurinburg (North Carolina) | 2,166.84 mi (3,487.19 km) |
| Rancho Santa Margarita to Lawndale (California) | 46.82 mi (75.34 km) |
| Rancho Santa Margarita to Lawrence (Indiana) | 1,792.03 mi (2,884.00 km) |
| Rancho Santa Margarita to Lawrence (Kansas) | 1,293.29 mi (2,081.35 km) |
| Rancho Santa Margarita to Lawrence (Massachusetts) | 2,565.23 mi (4,128.33 km) |
| Rancho Santa Margarita to Lawrenceburg (Kentucky) | 1,846.84 mi (2,972.21 km) |
| Rancho Santa Margarita to Lawrenceburg (Tennessee) | 1,721.60 mi (2,770.65 km) |
| Rancho Santa Margarita to Lawrenceville (Georgia) | 1,921.03 mi (3,091.60 km) |
| Rancho Santa Margarita to Lawton (Oklahoma) | 1,097.41 mi (1,766.12 km) |
| Rancho Santa Margarita to Layton (Utah) | 600.05 mi (965.69 km) |
| Rancho Santa Margarita to Le Mars (Iowa) | 1,318.50 mi (2,121.92 km) |
| Rancho Santa Margarita to League City (Texas) | 1,351.79 mi (2,175.50 km) |
| Rancho Santa Margarita to Lealman (Florida) | 2,101.96 mi (3,382.78 km) |
| Rancho Santa Margarita to Leander (Texas) | 1,172.47 mi (1,886.90 km) |
| Rancho Santa Margarita to Leavenworth (Kansas) | 1,315.60 mi (2,117.25 km) |
