| Rancho Santa Margarita to Laredo (Texas) | 1,153.84 mi (1,856.92 km) |
| Rancho Santa Margarita to Largo (Florida) | 2,094.91 mi (3,371.43 km) |
| Rancho Santa Margarita to Largo (Maryland) | 2,281.14 mi (3,671.14 km) |
| Rancho Santa Margarita to Larkspur (California) | 406.08 mi (653.52 km) |
| Rancho Santa Margarita to Las Cruces (New Mexico) | 632.68 mi (1,018.19 km) |
| Rancho Santa Margarita to Las Vegas (Nevada) | 223.09 mi (359.03 km) |
| Rancho Santa Margarita to Las Vegas (New Mexico) | 716.36 mi (1,152.87 km) |
| Rancho Santa Margarita to Latham (New York) | 2,433.88 mi (3,916.95 km) |
| Rancho Santa Margarita to Lathrop (California) | 355.89 mi (572.75 km) |
| Rancho Santa Margarita to Lauderdale Lakes (Florida) | 2,285.51 mi (3,678.18 km) |
| Rancho Santa Margarita to Lauderhill (Florida) | 2,284.43 mi (3,676.43 km) |
| Rancho Santa Margarita to Laurel (Florida) | 2,131.28 mi (3,429.97 km) |
| Rancho Santa Margarita to Laurel (Maryland) | 2,278.44 mi (3,666.79 km) |
| Rancho Santa Margarita to Laurel (Mississippi) | 1,655.26 mi (2,663.89 km) |
| Rancho Santa Margarita to Laurel (Virginia) | 2,251.24 mi (3,623.03 km) |
