| Rancho Santa Margarita to Lake Shore (Maryland) | 2,298.45 mi (3,699.00 km) |
| Rancho Santa Margarita to Lake St. Louis (Missouri) | 1,530.50 mi (2,463.11 km) |
| Rancho Santa Margarita to Lake Station (Indiana) | 1,738.54 mi (2,797.91 km) |
| Rancho Santa Margarita to Lake Stevens (Washington) | 1,019.90 mi (1,641.38 km) |
| Rancho Santa Margarita to Lake Stickney (Washington) | 1,013.27 mi (1,630.70 km) |
| Rancho Santa Margarita to Lake Tapps (Washington) | 969.40 mi (1,560.10 km) |
| Rancho Santa Margarita to Lake Wales (Florida) | 2,162.25 mi (3,479.81 km) |
| Rancho Santa Margarita to Lake Wylie (South Carolina) | 2,074.28 mi (3,338.23 km) |
| Rancho Santa Margarita to Lake Zurich (Illinois) | 1,703.67 mi (2,741.80 km) |
| Rancho Santa Margarita to Lakeland (Florida) | 2,138.50 mi (3,441.58 km) |
| Rancho Santa Margarita to Lakeland (Tennessee) | 1,586.66 mi (2,553.49 km) |
| Rancho Santa Margarita to Lakeland Highlands (Florida) | 2,141.05 mi (3,445.68 km) |
| Rancho Santa Margarita to Lakeland North (Washington) | 977.93 mi (1,573.83 km) |
| Rancho Santa Margarita to Lakeland South (Washington) | 974.05 mi (1,567.58 km) |
| Rancho Santa Margarita to Lakeland Village (California) | 13.17 mi (21.20 km) |
