| Rancho Santa Margarita to Lake Forest Park (Washington) | 1,005.91 mi (1,618.85 km) |
| Rancho Santa Margarita to Lake Grove (New York) | 2,469.77 mi (3,974.71 km) |
| Rancho Santa Margarita to Lake Havasu City (Arizona) | 197.50 mi (317.84 km) |
| Rancho Santa Margarita to Lake Hopatcong (New Jersey) | 2,391.61 mi (3,848.92 km) |
| Rancho Santa Margarita to Lake in the Hills (Illinois) | 1,690.50 mi (2,720.60 km) |
| Rancho Santa Margarita to Lake Jackson (Texas) | 1,341.79 mi (2,159.41 km) |
| Rancho Santa Margarita to Lake Los Angeles (California) | 68.89 mi (110.87 km) |
| Rancho Santa Margarita to Lake Magdalene (Florida) | 2,107.60 mi (3,391.85 km) |
| Rancho Santa Margarita to Lake Mary (Florida) | 2,158.41 mi (3,473.62 km) |
| Rancho Santa Margarita to Lake Monticello (Virginia) | 2,204.79 mi (3,548.26 km) |
| Rancho Santa Margarita to Lake Morton-Berrydale (Washington) | 975.33 mi (1,569.64 km) |
| Rancho Santa Margarita to Lake Norman of Catawba (North Carolina) | 2,074.48 mi (3,338.56 km) |
| Rancho Santa Margarita to Lake Oswego (Oregon) | 857.73 mi (1,380.39 km) |
| Rancho Santa Margarita to Lake Ridge (Virginia) | 2,256.35 mi (3,631.24 km) |
| Rancho Santa Margarita to Lake Ronkonkoma (New York) | 2,470.08 mi (3,975.22 km) |
