| Rancho Santa Margarita to La Quinta (California) | 75.96 mi (122.24 km) |
| Rancho Santa Margarita to La Riviera (California) | 400.27 mi (644.17 km) |
| Rancho Santa Margarita to La Vergne (Tennessee) | 1,760.82 mi (2,833.77 km) |
| Rancho Santa Margarita to La Verne (California) | 35.18 mi (56.62 km) |
| Rancho Santa Margarita to La Vista (Nebraska) | 1,287.26 mi (2,071.64 km) |
| Rancho Santa Margarita to Lacey (Washington) | 965.80 mi (1,554.31 km) |
| Rancho Santa Margarita to Lackawanna (New York) | 2,176.49 mi (3,502.72 km) |
| Rancho Santa Margarita to Laconia (New Hampshire) | 2,548.28 mi (4,101.06 km) |
| Rancho Santa Margarita to Ladera Ranch (California) | 6.22 mi (10.01 km) |
| Rancho Santa Margarita to Ladson (South Carolina) | 2,152.96 mi (3,464.86 km) |
| Rancho Santa Margarita to Lady Lake (Florida) | 2,120.70 mi (3,412.94 km) |
| Rancho Santa Margarita to Lafayette (California) | 388.30 mi (624.90 km) |
| Rancho Santa Margarita to Lafayette (Colorado) | 818.10 mi (1,316.61 km) |
| Rancho Santa Margarita to Lafayette (Indiana) | 1,749.33 mi (2,815.28 km) |
| Rancho Santa Margarita to Lafayette (Louisiana) | 1,513.93 mi (2,436.44 km) |
