| Rancho Santa Margarita to La Crescenta-Montrose (California) | 55.25 mi (88.91 km) |
| Rancho Santa Margarita to La Crosse (Wisconsin) | 1,576.96 mi (2,537.87 km) |
| Rancho Santa Margarita to La Grande (Oregon) | 808.28 mi (1,300.80 km) |
| Rancho Santa Margarita to La Grange (Illinois) | 1,709.76 mi (2,751.60 km) |
| Rancho Santa Margarita to La Grange Park (Illinois) | 1,710.13 mi (2,752.18 km) |
| Rancho Santa Margarita to La Habra (California) | 28.80 mi (46.36 km) |
| Rancho Santa Margarita to La Homa (Texas) | 1,256.19 mi (2,021.65 km) |
| Rancho Santa Margarita to La Marque (Texas) | 1,360.91 mi (2,190.17 km) |
| Rancho Santa Margarita to La Mesa (California) | 68.27 mi (109.88 km) |
| Rancho Santa Margarita to La Mirada (California) | 30.10 mi (48.43 km) |
| Rancho Santa Margarita to La Palma (California) | 29.54 mi (47.54 km) |
| Rancho Santa Margarita to La Porte (Indiana) | 1,766.78 mi (2,843.36 km) |
| Rancho Santa Margarita to La Porte (Texas) | 1,351.42 mi (2,174.90 km) |
| Rancho Santa Margarita to La Presa (California) | 72.36 mi (116.45 km) |
| Rancho Santa Margarita to La Puente (California) | 34.35 mi (55.28 km) |
