| Rancho Santa Margarita to Hutchinson (Kansas) | 1,142.06 mi (1,837.97 km) |
| Rancho Santa Margarita to Hutchinson (Minnesota) | 1,457.58 mi (2,345.75 km) |
| Rancho Santa Margarita to Hutto (Texas) | 1,191.30 mi (1,917.21 km) |
| Rancho Santa Margarita to Hyattsville (Maryland) | 2,274.03 mi (3,659.70 km) |
| Rancho Santa Margarita to Hybla Valley (Virginia) | 2,268.13 mi (3,650.21 km) |
| Rancho Santa Margarita to Idaho Falls (Idaho) | 743.85 mi (1,197.12 km) |
| Rancho Santa Margarita to Idylwood (Virginia) | 2,260.88 mi (3,638.53 km) |
| Rancho Santa Margarita to Ilchester (Maryland) | 2,282.97 mi (3,674.08 km) |
| Rancho Santa Margarita to Immokalee (Florida) | 2,208.59 mi (3,554.38 km) |
| Rancho Santa Margarita to Imperial (California) | 129.30 mi (208.09 km) |
| Rancho Santa Margarita to Imperial Beach (California) | 78.51 mi (126.35 km) |
| Rancho Santa Margarita to Independence (Kentucky) | 1,866.22 mi (3,003.40 km) |
| Rancho Santa Margarita to Independence (Missouri) | 1,343.13 mi (2,161.56 km) |
| Rancho Santa Margarita to Indian Trail (North Carolina) | 2,098.22 mi (3,376.77 km) |
| Rancho Santa Margarita to Indiana (Pennsylvania) | 2,154.15 mi (3,466.77 km) |
