| Rancho Santa Margarita to Home Gardens (California) | 17.75 mi (28.57 km) |
| Rancho Santa Margarita to Homer Glen (Illinois) | 1,703.64 mi (2,741.75 km) |
| Rancho Santa Margarita to Homestead (Florida) | 2,290.06 mi (3,685.50 km) |
| Rancho Santa Margarita to Homewood (Alabama) | 1,766.42 mi (2,842.78 km) |
| Rancho Santa Margarita to Homewood (Illinois) | 1,717.90 mi (2,764.69 km) |
| Rancho Santa Margarita to Homosassa Springs (Florida) | 2,088.06 mi (3,360.40 km) |
| Rancho Santa Margarita to Honeygo (Maryland) | 2,300.40 mi (3,702.14 km) |
| Rancho Santa Margarita to Honolulu (Hawaii) | 2,590.51 mi (4,169.03 km) |
| Rancho Santa Margarita to Hoover (Alabama) | 1,767.48 mi (2,844.49 km) |
| Rancho Santa Margarita to Hopatcong (New Jersey) | 2,389.02 mi (3,844.75 km) |
| Rancho Santa Margarita to Hope Mills (North Carolina) | 2,193.56 mi (3,530.20 km) |
| Rancho Santa Margarita to Hopewell (Virginia) | 2,264.91 mi (3,645.03 km) |
| Rancho Santa Margarita to Hopkins (Minnesota) | 1,502.27 mi (2,417.66 km) |
| Rancho Santa Margarita to Hopkinsville (Kentucky) | 1,707.14 mi (2,747.38 km) |
| Rancho Santa Margarita to Horizon City (Texas) | 676.83 mi (1,089.25 km) |
