| Rancho Santa Margarita to Finneytown (Ohio) | 1,868.49 mi (3,007.05 km) |
| Rancho Santa Margarita to Firestone (Colorado) | 830.45 mi (1,336.48 km) |
| Rancho Santa Margarita to Fish Hawk (Florida) | 2,128.16 mi (3,424.94 km) |
| Rancho Santa Margarita to Fishers (Indiana) | 1,793.76 mi (2,886.78 km) |
| Rancho Santa Margarita to Fitchburg (Massachusetts) | 2,532.26 mi (4,075.27 km) |
| Rancho Santa Margarita to Fitchburg (Wisconsin) | 1,648.52 mi (2,653.03 km) |
| Rancho Santa Margarita to Five Corners (Washington) | 873.58 mi (1,405.89 km) |
| Rancho Santa Margarita to Five Forks (South Carolina) | 2,012.03 mi (3,238.05 km) |
| Rancho Santa Margarita to Flagstaff (Arizona) | 357.32 mi (575.04 km) |
| Rancho Santa Margarita to Flat Rock (Michigan) | 1,946.78 mi (3,133.04 km) |
| Rancho Santa Margarita to Fleming Island (Florida) | 2,109.41 mi (3,394.77 km) |
| Rancho Santa Margarita to Flint (Michigan) | 1,933.46 mi (3,111.61 km) |
| Rancho Santa Margarita to Floral Park (New York) | 2,439.62 mi (3,926.20 km) |
| Rancho Santa Margarita to Florence (Alabama) | 1,705.60 mi (2,744.90 km) |
| Rancho Santa Margarita to Florence (Arizona) | 358.71 mi (577.29 km) |
