| Rancho Santa Margarita to Duluth (Minnesota) | 1,610.06 mi (2,591.14 km) |
| Rancho Santa Margarita to Dumas (Texas) | 899.87 mi (1,448.19 km) |
| Rancho Santa Margarita to Dumont (New Jersey) | 2,423.82 mi (3,900.77 km) |
| Rancho Santa Margarita to Duncan (Oklahoma) | 1,125.96 mi (1,812.06 km) |
| Rancho Santa Margarita to Duncanville (Texas) | 1,196.74 mi (1,925.97 km) |
| Rancho Santa Margarita to Dundalk (Maryland) | 2,297.41 mi (3,697.32 km) |
| Rancho Santa Margarita to Dunedin (Florida) | 2,091.18 mi (3,365.43 km) |
| Rancho Santa Margarita to Dunkirk (New York) | 2,149.61 mi (3,459.47 km) |
| Rancho Santa Margarita to Dunmore (Pennsylvania) | 2,339.04 mi (3,764.32 km) |
| Rancho Santa Margarita to Dunwoody (Georgia) | 1,903.08 mi (3,062.70 km) |
| Rancho Santa Margarita to Durango (Colorado) | 601.59 mi (968.17 km) |
| Rancho Santa Margarita to Durant (Oklahoma) | 1,215.47 mi (1,956.12 km) |
| Rancho Santa Margarita to Durham (North Carolina) | 2,186.99 mi (3,519.61 km) |
| Rancho Santa Margarita to Dyer (Indiana) | 1,725.03 mi (2,776.17 km) |
| Rancho Santa Margarita to Dyersburg (Tennessee) | 1,603.44 mi (2,580.48 km) |
