| Rancho Santa Margarita to Dover (New Hampshire) | 2,578.42 mi (4,149.57 km) |
| Rancho Santa Margarita to Dover (New Jersey) | 2,394.38 mi (3,853.37 km) |
| Rancho Santa Margarita to Dover (Ohio) | 2,032.01 mi (3,270.21 km) |
| Rancho Santa Margarita to Downers Grove (Illinois) | 1,702.36 mi (2,739.68 km) |
| Rancho Santa Margarita to Downey (California) | 37.17 mi (59.82 km) |
| Rancho Santa Margarita to Dranesville (Virginia) | 2,251.67 mi (3,623.71 km) |
| Rancho Santa Margarita to Draper (Utah) | 569.78 mi (916.97 km) |
| Rancho Santa Margarita to Drexel Heights (Arizona) | 393.63 mi (633.48 km) |
| Rancho Santa Margarita to Drexel Hill (Pennsylvania) | 2,358.11 mi (3,795.01 km) |
| Rancho Santa Margarita to Duarte (California) | 41.76 mi (67.20 km) |
| Rancho Santa Margarita to Dublin (California) | 371.14 mi (597.29 km) |
| Rancho Santa Margarita to Dublin (Georgia) | 1,999.15 mi (3,217.32 km) |
| Rancho Santa Margarita to Dublin (Ohio) | 1,943.32 mi (3,127.47 km) |
| Rancho Santa Margarita to Dubuque (Iowa) | 1,577.37 mi (2,538.53 km) |
| Rancho Santa Margarita to Duluth (Georgia) | 1,911.64 mi (3,076.48 km) |
