| Rancho Santa Margarita to Cullman (Alabama) | 1,757.50 mi (2,828.43 km) |
| Rancho Santa Margarita to Culpeper (Virginia) | 2,219.93 mi (3,572.64 km) |
| Rancho Santa Margarita to Culver City (California) | 52.59 mi (84.64 km) |
| Rancho Santa Margarita to Cumberland (Maryland) | 2,175.65 mi (3,501.37 km) |
| Rancho Santa Margarita to Cupertino (California) | 356.92 mi (574.41 km) |
| Rancho Santa Margarita to Cutler Bay (Florida) | 2,293.49 mi (3,691.01 km) |
| Rancho Santa Margarita to Cutlerville (Michigan) | 1,832.48 mi (2,949.09 km) |
| Rancho Santa Margarita to Cuyahoga Falls (Ohio) | 2,031.80 mi (3,269.86 km) |
| Rancho Santa Margarita to Cypress (California) | 28.33 mi (45.59 km) |
| Rancho Santa Margarita to Cypress Gardens (Florida) | 2,155.16 mi (3,468.39 km) |
| Rancho Santa Margarita to Cypress Lake (Florida) | 2,178.40 mi (3,505.80 km) |
| Rancho Santa Margarita to D'Iberville (Mississippi) | 1,689.26 mi (2,718.60 km) |
| Rancho Santa Margarita to Dakota Ridge (Colorado) | 804.37 mi (1,294.51 km) |
| Rancho Santa Margarita to Dale City (Virginia) | 2,254.40 mi (3,628.11 km) |
| Rancho Santa Margarita to Dallas (Georgia) | 1,873.36 mi (3,014.88 km) |
