| Rancho Santa Margarita to Cordele (Georgia) | 1,959.55 mi (3,153.59 km) |
| Rancho Santa Margarita to Corinth (Mississippi) | 1,656.94 mi (2,666.59 km) |
| Rancho Santa Margarita to Corinth (Texas) | 1,182.96 mi (1,903.79 km) |
| Rancho Santa Margarita to Cornelius (North Carolina) | 2,081.31 mi (3,349.54 km) |
| Rancho Santa Margarita to Cornelius (Oregon) | 870.58 mi (1,401.07 km) |
| Rancho Santa Margarita to Corning (New York) | 2,264.76 mi (3,644.79 km) |
| Rancho Santa Margarita to Corona (California) | 16.00 mi (25.74 km) |
| Rancho Santa Margarita to Coronado (California) | 71.46 mi (115.00 km) |
| Rancho Santa Margarita to Corpus Christi (Texas) | 1,266.48 mi (2,038.20 km) |
| Rancho Santa Margarita to Corsicana (Texas) | 1,229.04 mi (1,977.96 km) |
| Rancho Santa Margarita to Cortland (New York) | 2,310.38 mi (3,718.20 km) |
| Rancho Santa Margarita to Corvallis (Oregon) | 814.25 mi (1,310.41 km) |
| Rancho Santa Margarita to Coshocton (Ohio) | 2,012.12 mi (3,238.19 km) |
| Rancho Santa Margarita to Costa Mesa (California) | 18.26 mi (29.39 km) |
| Rancho Santa Margarita to Coto de Caza (California) | 2.59 mi (4.16 km) |
