| Rancho Santa Margarita to Cold Springs (Nevada) | 438.98 mi (706.47 km) |
| Rancho Santa Margarita to Coldwater (Michigan) | 1,857.50 mi (2,989.36 km) |
| Rancho Santa Margarita to Colesville (Maryland) | 2,271.09 mi (3,654.97 km) |
| Rancho Santa Margarita to College (Alaska) | 2,501.17 mi (4,025.25 km) |
| Rancho Santa Margarita to College Park (Georgia) | 1,897.80 mi (3,054.21 km) |
| Rancho Santa Margarita to College Park (Maryland) | 2,275.02 mi (3,661.28 km) |
| Rancho Santa Margarita to College Station (Texas) | 1,262.06 mi (2,031.09 km) |
| Rancho Santa Margarita to Collegedale (Tennessee) | 1,851.33 mi (2,979.42 km) |
| Rancho Santa Margarita to Colleyville (Texas) | 1,180.68 mi (1,900.12 km) |
| Rancho Santa Margarita to Collierville (Tennessee) | 1,589.56 mi (2,558.15 km) |
| Rancho Santa Margarita to Collinsville (Illinois) | 1,571.92 mi (2,529.76 km) |
| Rancho Santa Margarita to Colonia (New Jersey) | 2,408.01 mi (3,875.32 km) |
| Rancho Santa Margarita to Colonial Heights (Virginia) | 2,259.72 mi (3,636.67 km) |
| Rancho Santa Margarita to Colonial Park (Pennsylvania) | 2,277.80 mi (3,665.77 km) |
| Rancho Santa Margarita to Colorado Springs (Colorado) | 800.57 mi (1,288.39 km) |
