| Rancho Santa Margarita to Chicago Ridge (Illinois) | 1,713.41 mi (2,757.47 km) |
| Rancho Santa Margarita to Chickasha (Oklahoma) | 1,123.57 mi (1,808.21 km) |
| Rancho Santa Margarita to Chico (California) | 483.32 mi (777.82 km) |
| Rancho Santa Margarita to Chicopee (Massachusetts) | 2,494.40 mi (4,014.35 km) |
| Rancho Santa Margarita to Chillicothe (Ohio) | 1,949.97 mi (3,138.17 km) |
| Rancho Santa Margarita to Chillum (Maryland) | 2,272.71 mi (3,657.57 km) |
| Rancho Santa Margarita to Chino (California) | 24.61 mi (39.60 km) |
| Rancho Santa Margarita to Chino Hills (California) | 23.21 mi (37.35 km) |
| Rancho Santa Margarita to Chino Valley (Arizona) | 306.44 mi (493.18 km) |
| Rancho Santa Margarita to Chippewa Falls (Wisconsin) | 1,594.20 mi (2,565.62 km) |
| Rancho Santa Margarita to Choctaw (Oklahoma) | 1,161.92 mi (1,869.93 km) |
| Rancho Santa Margarita to Chowchilla (California) | 282.45 mi (454.56 km) |
| Rancho Santa Margarita to Christiansburg (Virginia) | 2,095.76 mi (3,372.80 km) |
| Rancho Santa Margarita to Chubbuck (Idaho) | 699.65 mi (1,125.98 km) |
| Rancho Santa Margarita to Chula Vista (California) | 77.15 mi (124.17 km) |
