| Rancho Santa Margarita to Cedar Park (Texas) | 1,176.04 mi (1,892.65 km) |
| Rancho Santa Margarita to Cedar Rapids (Iowa) | 1,520.30 mi (2,446.69 km) |
| Rancho Santa Margarita to Cedarburg (Wisconsin) | 1,723.98 mi (2,774.47 km) |
| Rancho Santa Margarita to Celebration (Florida) | 2,155.94 mi (3,469.65 km) |
| Rancho Santa Margarita to Celina (Ohio) | 1,870.51 mi (3,010.30 km) |
| Rancho Santa Margarita to Celina (Texas) | 1,197.22 mi (1,926.74 km) |
| Rancho Santa Margarita to Centennial (Colorado) | 816.25 mi (1,313.63 km) |
| Rancho Santa Margarita to Center Point (Alabama) | 1,771.52 mi (2,850.98 km) |
| Rancho Santa Margarita to Centereach (New York) | 2,471.55 mi (3,977.57 km) |
| Rancho Santa Margarita to Centerton (Arkansas) | 1,328.99 mi (2,138.81 km) |
| Rancho Santa Margarita to Centerville (Ohio) | 1,889.10 mi (3,040.22 km) |
| Rancho Santa Margarita to Centerville (Utah) | 593.67 mi (955.43 km) |
| Rancho Santa Margarita to Central (Louisiana) | 1,564.83 mi (2,518.34 km) |
| Rancho Santa Margarita to Central Falls (Rhode Island) | 2,555.55 mi (4,112.76 km) |
| Rancho Santa Margarita to Central Islip (New York) | 2,465.98 mi (3,968.62 km) |
