| Rancho Santa Margarita to Candler-McAfee (Georgia) | 1,907.67 mi (3,070.10 km) |
| Rancho Santa Margarita to Caño Martin Peña (Puerto Rico) | 3,331.45 mi (5,361.45 km) |
| Rancho Santa Margarita to Cañon City (Colorado) | 766.45 mi (1,233.48 km) |
| Rancho Santa Margarita to Canóvanas (Puerto Rico) | 3,342.10 mi (5,378.59 km) |
| Rancho Santa Margarita to Canton (Georgia) | 1,889.92 mi (3,041.53 km) |
| Rancho Santa Margarita to Canton (Illinois) | 1,584.86 mi (2,550.59 km) |
| Rancho Santa Margarita to Canton (Mississippi) | 1,592.23 mi (2,562.45 km) |
| Rancho Santa Margarita to Canton (Ohio) | 2,038.63 mi (3,280.86 km) |
| Rancho Santa Margarita to Canyon (Texas) | 898.83 mi (1,446.52 km) |
| Rancho Santa Margarita to Canyon Lake (California) | 19.76 mi (31.79 km) |
| Rancho Santa Margarita to Canyon Lake (Texas) | 1,163.47 mi (1,872.43 km) |
| Rancho Santa Margarita to Cape Coral (Florida) | 2,170.22 mi (3,492.64 km) |
| Rancho Santa Margarita to Cape Girardeau (Missouri) | 1,592.11 mi (2,562.26 km) |
| Rancho Santa Margarita to Carbondale (Illinois) | 1,611.07 mi (2,592.76 km) |
| Rancho Santa Margarita to Carlisle (Pennsylvania) | 2,257.08 mi (3,632.42 km) |
