| Rancho Santa Margarita to Cadillac (Michigan) | 1,863.44 mi (2,998.92 km) |
| Rancho Santa Margarita to Caguas (Puerto Rico) | 3,338.82 mi (5,373.31 km) |
| Rancho Santa Margarita to Cahokia (Illinois) | 1,562.04 mi (2,513.85 km) |
| Rancho Santa Margarita to Calabasas (California) | 70.63 mi (113.66 km) |
| Rancho Santa Margarita to Caldwell (Idaho) | 693.71 mi (1,116.41 km) |
| Rancho Santa Margarita to Caledonia (Wisconsin) | 1,722.22 mi (2,771.65 km) |
| Rancho Santa Margarita to Calera (Alabama) | 1,773.86 mi (2,854.75 km) |
| Rancho Santa Margarita to Calexico (California) | 138.19 mi (222.39 km) |
| Rancho Santa Margarita to Calhoun (Georgia) | 1,862.25 mi (2,997.00 km) |
| Rancho Santa Margarita to California (Maryland) | 2,302.12 mi (3,704.90 km) |
| Rancho Santa Margarita to California City (California) | 106.58 mi (171.53 km) |
| Rancho Santa Margarita to Callaway (Florida) | 1,887.77 mi (3,038.08 km) |
| Rancho Santa Margarita to Calumet City (Illinois) | 1,724.11 mi (2,774.69 km) |
| Rancho Santa Margarita to Calverton (Maryland) | 2,273.95 mi (3,659.57 km) |
| Rancho Santa Margarita to Camano (Washington) | 1,036.76 mi (1,668.50 km) |
