| Rancho Santa Margarita to Ashtabula (Ohio) | 2,072.03 mi (3,334.61 km) |
| Rancho Santa Margarita to Ashwaubenon (Wisconsin) | 1,738.96 mi (2,798.59 km) |
| Rancho Santa Margarita to Aspen Hill (Maryland) | 2,266.65 mi (3,647.82 km) |
| Rancho Santa Margarita to Astoria (Oregon) | 926.91 mi (1,491.72 km) |
| Rancho Santa Margarita to Atascadero (California) | 217.26 mi (349.64 km) |
| Rancho Santa Margarita to Atascocita (Texas) | 1,336.73 mi (2,151.26 km) |
| Rancho Santa Margarita to Atchison (Kansas) | 1,307.53 mi (2,104.26 km) |
| Rancho Santa Margarita to Athens (Alabama) | 1,746.29 mi (2,810.38 km) |
| Rancho Santa Margarita to Athens (Georgia) | 1,956.39 mi (3,148.50 km) |
| Rancho Santa Margarita to Athens (Ohio) | 1,997.80 mi (3,215.15 km) |
| Rancho Santa Margarita to Athens (Tennessee) | 1,873.28 mi (3,014.75 km) |
| Rancho Santa Margarita to Athens (Texas) | 1,263.99 mi (2,034.20 km) |
| Rancho Santa Margarita to Atlanta (Georgia) | 1,898.78 mi (3,055.79 km) |
| Rancho Santa Margarita to Atlantic Beach (Florida) | 2,122.10 mi (3,415.18 km) |
| Rancho Santa Margarita to Atlantic City (New Jersey) | 2,405.78 mi (3,871.73 km) |
