| Rancho Santa Margarita to Anderson (California) | 537.36 mi (864.80 km) |
| Rancho Santa Margarita to Anderson (Indiana) | 1,809.00 mi (2,911.31 km) |
| Rancho Santa Margarita to Anderson (South Carolina) | 1,991.15 mi (3,204.44 km) |
| Rancho Santa Margarita to Anderson Creek (North Carolina) | 2,190.60 mi (3,525.43 km) |
| Rancho Santa Margarita to Andover (Kansas) | 1,179.84 mi (1,898.77 km) |
| Rancho Santa Margarita to Andover (Minnesota) | 1,514.84 mi (2,437.90 km) |
| Rancho Santa Margarita to Andrews (Texas) | 876.05 mi (1,409.87 km) |
| Rancho Santa Margarita to Angleton (Texas) | 1,340.37 mi (2,157.12 km) |
| Rancho Santa Margarita to Ankeny (Iowa) | 1,420.29 mi (2,285.74 km) |
| Rancho Santa Margarita to Ann Arbor (Michigan) | 1,924.78 mi (3,097.63 km) |
| Rancho Santa Margarita to Anna (Texas) | 1,210.91 mi (1,948.77 km) |
| Rancho Santa Margarita to Annandale (Virginia) | 2,261.64 mi (3,639.76 km) |
| Rancho Santa Margarita to Annapolis (Maryland) | 2,298.12 mi (3,698.47 km) |
| Rancho Santa Margarita to Annapolis Neck (Maryland) | 2,298.53 mi (3,699.12 km) |
| Rancho Santa Margarita to Anniston (Alabama) | 1,820.78 mi (2,930.27 km) |
