| Rancho Santa Margarita to Allison Park (Pennsylvania) | 2,111.87 mi (3,398.73 km) |
| Rancho Santa Margarita to Allouez (Wisconsin) | 1,741.82 mi (2,803.19 km) |
| Rancho Santa Margarita to Aloha (Oregon) | 865.76 mi (1,393.31 km) |
| Rancho Santa Margarita to Alpena (Michigan) | 1,970.22 mi (3,170.76 km) |
| Rancho Santa Margarita to Alpharetta (Georgia) | 1,903.91 mi (3,064.04 km) |
| Rancho Santa Margarita to Alpine (California) | 72.95 mi (117.40 km) |
| Rancho Santa Margarita to Alpine (Utah) | 570.65 mi (918.37 km) |
| Rancho Santa Margarita to Alsip (Illinois) | 1,715.22 mi (2,760.38 km) |
| Rancho Santa Margarita to Altadena (California) | 49.45 mi (79.59 km) |
| Rancho Santa Margarita to Altamont (Oregon) | 632.94 mi (1,018.62 km) |
| Rancho Santa Margarita to Altamonte Springs (Florida) | 2,157.12 mi (3,471.55 km) |
| Rancho Santa Margarita to Alton (Illinois) | 1,565.35 mi (2,519.19 km) |
| Rancho Santa Margarita to Alton (Texas) | 1,258.51 mi (2,025.37 km) |
| Rancho Santa Margarita to Altoona (Iowa) | 1,425.05 mi (2,293.40 km) |
| Rancho Santa Margarita to Altoona (Pennsylvania) | 2,193.73 mi (3,530.48 km) |
