| Rancho Santa Margarita to Alderwood Manor (Washington) | 1,009.47 mi (1,624.59 km) |
| Rancho Santa Margarita to Aldine (Texas) | 1,327.54 mi (2,136.48 km) |
| Rancho Santa Margarita to Alexander City (Alabama) | 1,822.45 mi (2,932.95 km) |
| Rancho Santa Margarita to Alexandria (Louisiana) | 1,470.19 mi (2,366.04 km) |
| Rancho Santa Margarita to Alexandria (Minnesota) | 1,444.19 mi (2,324.19 km) |
| Rancho Santa Margarita to Alexandria (Virginia) | 2,267.60 mi (3,649.36 km) |
| Rancho Santa Margarita to Algonquin (Illinois) | 1,691.74 mi (2,722.59 km) |
| Rancho Santa Margarita to Alhambra (California) | 43.87 mi (70.60 km) |
| Rancho Santa Margarita to Alice (Texas) | 1,227.14 mi (1,974.90 km) |
| Rancho Santa Margarita to Aliso Viejo (California) | 8.32 mi (13.39 km) |
| Rancho Santa Margarita to Allen (Texas) | 1,205.92 mi (1,940.74 km) |
| Rancho Santa Margarita to Allen Park (Michigan) | 1,951.08 mi (3,139.96 km) |
| Rancho Santa Margarita to Allendale (Michigan) | 1,820.40 mi (2,929.65 km) |
| Rancho Santa Margarita to Allentown (Pennsylvania) | 2,347.15 mi (3,777.37 km) |
| Rancho Santa Margarita to Alliance (Ohio) | 2,051.90 mi (3,302.22 km) |
