| Rancho Santa Margarita to Enniskillen | 5,076.97 mi (8,170.59 km) |
| Rancho Santa Margarita to Epping | 5,442.59 mi (8,759.00 km) |
| Rancho Santa Margarita to Epsom | 5,447.01 mi (8,766.11 km) |
| Rancho Santa Margarita to Erdington | 5,342.86 mi (8,598.50 km) |
| Rancho Santa Margarita to Erith | 5,454.87 mi (8,778.77 km) |
| Rancho Santa Margarita to Esher | 5,442.32 mi (8,758.56 km) |
| Rancho Santa Margarita to Euxton | 5,266.14 mi (8,475.03 km) |
| Rancho Santa Margarita to Evesham | 5,358.39 mi (8,623.49 km) |
| Rancho Santa Margarita to Evington | 5,363.15 mi (8,631.16 km) |
| Rancho Santa Margarita to Ewell | 5,446.96 mi (8,766.03 km) |
| Rancho Santa Margarita to Exeter | 5,365.57 mi (8,635.04 km) |
| Rancho Santa Margarita to Exmouth | 5,374.03 mi (8,648.67 km) |
| Rancho Santa Margarita to Failsworth | 5,289.19 mi (8,512.13 km) |
| Rancho Santa Margarita to Falkirk | 5,131.27 mi (8,257.98 km) |
| Rancho Santa Margarita to Falmouth | 5,337.08 mi (8,589.21 km) |
