| Rancho Santa Margarita to Eckington | 5,323.25 mi (8,566.95 km) |
| Rancho Santa Margarita to Edgware | 5,434.00 mi (8,745.17 km) |
| Rancho Santa Margarita to Edinburgh | 5,151.42 mi (8,290.41 km) |
| Rancho Santa Margarita to Edmonton | 5,440.67 mi (8,755.92 km) |
| Rancho Santa Margarita to Egg Buckland | 5,359.53 mi (8,625.33 km) |
| Rancho Santa Margarita to Elgin | 5,075.66 mi (8,168.49 km) |
| Rancho Santa Margarita to Elland | 5,291.65 mi (8,516.09 km) |
| Rancho Santa Margarita to Ellesmere Port | 5,275.63 mi (8,490.31 km) |
| Rancho Santa Margarita to Ellon | 5,123.65 mi (8,245.72 km) |
| Rancho Santa Margarita to Eltham | 5,452.13 mi (8,774.35 km) |
| Rancho Santa Margarita to Ely | 5,415.69 mi (8,715.71 km) |
| Rancho Santa Margarita to Emsworth | 5,447.01 mi (8,766.11 km) |
| Rancho Santa Margarita to Enfield | 5,438.68 mi (8,752.70 km) |
| Rancho Santa Margarita to Enfield Lock | 5,439.70 mi (8,754.35 km) |
| Rancho Santa Margarita to Englefield Green | 5,432.88 mi (8,743.38 km) |
