| Rancho Santa Margarita to Selargius | 6,358.54 mi (10,233.07 km) |
| Rancho Santa Margarita to Selvazzano Dentro | 6,126.55 mi (9,859.73 km) |
| Rancho Santa Margarita to Senago | 6,031.91 mi (9,707.43 km) |
| Rancho Santa Margarita to Senigallia | 6,260.51 mi (10,075.32 km) |
| Rancho Santa Margarita to Seravezza | 6,149.57 mi (9,896.78 km) |
| Rancho Santa Margarita to Seregno | 6,030.64 mi (9,705.37 km) |
| Rancho Santa Margarita to Seriate | 6,045.48 mi (9,729.25 km) |
| Rancho Santa Margarita to Sermoneta | 6,368.86 mi (10,249.69 km) |
| Rancho Santa Margarita to Serramanna | 6,341.31 mi (10,205.36 km) |
| Rancho Santa Margarita to Serravalle Pistoiese | 6,174.34 mi (9,936.65 km) |
| Rancho Santa Margarita to Sessa Aurunca | 6,416.83 mi (10,326.89 km) |
| Rancho Santa Margarita to Sesto Calende | 6,008.04 mi (9,669.00 km) |
| Rancho Santa Margarita to Sesto Fiorentino | 6,189.73 mi (9,961.40 km) |
| Rancho Santa Margarita to Sesto San Giovanni | 6,037.72 mi (9,716.77 km) |
| Rancho Santa Margarita to Sestri Levante | 6,107.86 mi (9,829.64 km) |
