| Raleigh to Southern Pines (North Carolina) | 61.52 mi (99.01 km) |
| Raleigh to Southfield (Michigan) | 521.28 mi (838.91 km) |
| Raleigh to Southgate (Michigan) | 503.63 mi (810.52 km) |
| Raleigh to Southlake (Texas) | 1,072.05 mi (1,725.29 km) |
| Raleigh to Spanaway (Washington) | 2,361.44 mi (3,800.36 km) |
| Raleigh to Spanish Fork (Utah) | 1,810.81 mi (2,914.22 km) |
| Raleigh to Spanish Lake (Missouri) | 666.98 mi (1,073.41 km) |
| Raleigh to Spanish Springs (Nevada) | 2,237.49 mi (3,600.89 km) |
| Raleigh to Sparks (Nevada) | 2,240.61 mi (3,605.92 km) |
| Raleigh to Spartanburg (South Carolina) | 194.79 mi (313.48 km) |
| Raleigh to Spearfish (South Dakota) | 1,449.88 mi (2,333.36 km) |
| Raleigh to Speedway (Indiana) | 496.95 mi (799.76 km) |
| Raleigh to Spencer (Iowa) | 1,012.46 mi (1,629.40 km) |
| Raleigh to Spokane (Washington) | 2,132.97 mi (3,432.68 km) |
| Raleigh to Spokane Valley (Washington) | 2,123.79 mi (3,417.91 km) |
